Endocannabinoids are diffusible lipophilic molecules that may spread to neighboring
synapses. Monoacylglycerol lipase (MAGL) is the principal enzyme that degrades the …

Abstract The endocannabinoid 2-arachidonoylglycerol (2-AG) mediates retrograde synaptic
depression including depolarization-induced suppression of excitation (DSE) and inhibition …

The endocannabinoid 2-arachidonoylglycerol (2-AG) mediates retrograde synaptic
suppression. Although the mechanisms of 2-AG production are well characterized, how 2 …

Non‐Technical Summary 2‐Arachidonoylglycerol (2‐AG) is an endogenous marijuana‐like
chemical that regulates synaptic transmission via the stimulation of the type I cannabinoid …

Endocannabinoids function as retrograde messengers and modulate synaptic transmission
through presynaptic cannabinoid CB1 receptors. The magnitude and time course of …

Summary The endocannabinoid 2-arachidonoylglycerol (2-AG) is a retrograde lipid
messenger that modulates synaptic function, neurophysiology, and behavior. 2-AG signaling …

Endocannabinoids are released from postsynaptic neurons and cause retrograde
suppression of synaptic transmission. Anandamide and 2-arachidonoylglycerol (2-AG) are …

Activation of group I metabotropic glutamate (mGlu) receptors recruits the endocannabinoid
system to produce both short-and long-term changes in synaptic strength in many regions of …

Endocannabinoids play central roles in retrograde signaling at a wide variety of synapses
throughout the CNS. Although several molecular components of the endocannabinoid …

Depolarization-induced suppression of excitation (DSE) is a major form of cannabinoid-
mediated short-term retrograde neuronal plasticity and is found in numerous brain regions …