Multiscale aspects of generation of high-gamma activity during seizures in human neocortex
TL Eissa, AK Tryba, CJ Marcuccilli, F Ben-Mabrouk… - Eneuro, 2016 - eneuro.org
High-gamma (HG; 80-150 Hz) activity in macroscopic clinical records is considered a marker
for critical brain regions involved in seizure initiation; it is correlated with pathological …
for critical brain regions involved in seizure initiation; it is correlated with pathological …
Tracking multisite seizure propagation using ictal high-gamma activity
S Tobochnik, LM Bateman, CI Akman… - Journal of Clinical …, 2022 - journals.lww.com
Purpose: Spatial patterns of long-range seizure propagation in epileptic networks have not
been well characterized. Here, we use ictal high-gamma activity (HGA) as a proxy of intense …
been well characterized. Here, we use ictal high-gamma activity (HGA) as a proxy of intense …
Gamma oscillations precede interictal epileptiform spikes in the seizure onset zone
L Ren, MT Kucewicz, J Cimbalnik, JY Matsumoto… - Neurology, 2015 - AAN Enterprises
Objective: To investigate the generation, spectral characteristics, and potential clinical
significance of brain activity preceding interictal epileptiform spike discharges (IEDs) …
significance of brain activity preceding interictal epileptiform spike discharges (IEDs) …
Cortical activation in generalized seizures
L Ding, S Satish, C Zhou, MJ Gallagher - Epilepsia, 2019 - Wiley Online Library
Objective Patients with generalized epilepsy exhibit different epileptiform events including
asymptomatic interictal spikes (IS), absence seizures with spike‐wave discharges (SWD s) …
asymptomatic interictal spikes (IS), absence seizures with spike‐wave discharges (SWD s) …
[HTML][HTML] Local changes in neocortical circuit dynamics coincide with the spread of seizures to thalamus in a model of epilepsy
During the generalization of epileptic seizures, pathological activity in one brain area
recruits distant brain structures into joint synchronous discharges. However, it remains …
recruits distant brain structures into joint synchronous discharges. However, it remains …
Ictal high-gamma oscillation (60–99 Hz) in intracranial electroencephalography and postoperative seizure outcome in neocortical epilepsy
SC Park, SK Lee, H Che, CK Chung - Clinical neurophysiology, 2012 - Elsevier
OBJECTIVE: High-gamma oscillations (HGOs)(60–99Hz) have been suggested to correlate
with seizure onset zones and seizure outcomes. We investigated the correlation between …
with seizure onset zones and seizure outcomes. We investigated the correlation between …
[HTML][HTML] Distinguishing mechanisms of gamma frequency oscillations in human current source signals using a computational model of a laminar neocortical network
Gamma frequency rhythms have been implicated in numerous studies for their role in
healthy and abnormal brain function. The frequency band has been described to …
healthy and abnormal brain function. The frequency band has been described to …
Network asynchrony underlying increased broadband gamma power
Synchronous activity of cortical inhibitory interneurons expressing parvalbumin (PV)
underlies expression of cortical γ rhythms. Paradoxically, deficient PV inhibition is …
underlies expression of cortical γ rhythms. Paradoxically, deficient PV inhibition is …
Neocortical gamma oscillations in idiopathic generalized epilepsy
Objective Absence seizures in patients with idiopathic generalized epilepsy (IGE) may in
part be explained by a decrease in phasic GABAA (type‐A γ‐aminobutyric acid) receptor …
part be explained by a decrease in phasic GABAA (type‐A γ‐aminobutyric acid) receptor …
[HTML][HTML] Interaction between synaptic inhibition and glial-potassium dynamics leads to diverse seizure transition modes in biophysical models of human focal seizures
EC Y. Ho, W Truccolo - Journal of Computational Neuroscience, 2016 - Springer
How focal seizures initiate and evolve in human neocortex remains a fundamental problem
in neuroscience. Here, we use biophysical neuronal network models of neocortical patches …
in neuroscience. Here, we use biophysical neuronal network models of neocortical patches …