Interactions between dorsal and ventral root stimulation on the generation of locomotor-like activity in the neonatal mouse spinal cord

A Pujala, D Blivis, MJ O'Donovan - eneuro, 2016 - eneuro.org
We investigated whether dorsal (DR) and ventral root (VR) stimulus trains engage common
postsynaptic components to activate the central pattern generator (CPG) for locomotion in …

Excitatory actions of ventral root stimulation during network activity generated by the disinhibited neonatal mouse spinal cord

A Bonnot, N Chub, A Pujala… - Journal of …, 2009 - journals.physiology.org
To further understand the excitatory effects of motoneurons on spinal network function, we
investigated the entrainment of disinhibited rhythms by ventral root (VR) stimulation in the …

Propriospinal neurons are sufficient for bulbospinal transmission of the locomotor command signal in the neonatal rat spinal cord

KC Cowley, E Zaporozhets… - The Journal of …, 2008 - Wiley Online Library
We recently showed that propriospinal neurons contribute to bulbospinal activation of
locomotor networks in the in vitro neonatal rat brainstem–spinal cord preparation. In the …

Propriospinal neurons contribute to bulbospinal transmission of the locomotor command signal in the neonatal rat spinal cord

E Zaporozhets, KC Cowley… - The Journal of …, 2006 - Wiley Online Library
This study examines whether propriospinal transmission contributes to descending
propagation of the brainstem locomotor command signal in the in vitro neonatal rat spinal …

Synergistic interaction between sensory inputs and propriospinal signalling underlying quadrupedal locomotion

M Boulain, I Khsime, M Sourioux… - The Journal of …, 2021 - Wiley Online Library
Key points Stimulation of hindlimb afferent fibres can both stabilize and increase the activity
of fore‐and hindlimb motoneurons during fictive locomotion. The increase in motoneuron …

Brainstem modulation of locomotion in the neonatal mouse spinal cord

IT Gordon, PJ Whelan - The Journal of physiology, 2008 - Wiley Online Library
During development, descending projections to the spinal cord are immature. Available data
suggest that even though these projections are not fully formed, they contribute to activation …

Removing sensory input disrupts spinal locomotor activity in the early postnatal period

JM Acevedo, M Díaz-Ríos - Journal of Comparative Physiology A, 2013 - Springer
Motor patterns driving rhythmic movements of our lower limbs during walking are generated
by groups of neurons within the spinal cord, called central pattern generators (CPGs). After …

Contribution of commissural projections to bulbospinal activation of locomotion in the in vitro neonatal rat spinal cord

KC Cowley, E Zaporozhets… - Journal of …, 2009 - journals.physiology.org
Commissural projections are required for left-right coordination during locomotion. However,
their role, if any, in rhythm production is unknown. This study uses the neonatal rat in vitro …

Primary afferent terminals acting as excitatory interneurons contribute to spontaneous motor activities in the immature spinal cord

R Bos, F Brocard, L Vinay - Journal of Neuroscience, 2011 - Soc Neuroscience
Patterned, spontaneous activity plays a critical role in the development of neuronal
networks. A robust spontaneous activity is observed in vitro in spinal cord preparations …

[PDF][PDF] Spatiotemporal pattern of motoneuron activation in the rostral lumbar and the sacral segments during locomotor-like activity in the neonatal mouse spinal cord

A Bonnot, PJ Whelan, GZ Mentis… - The Journal of …, 2002 - Soc Neuroscience
We used calcium imaging to visualize the spatiotemporal pattern of motoneuron activity
during dorsal root-evoked locomotor-like bursting in the lumbosacral spinal cord of the …