[HTML][HTML] The molecular biology of susceptibility to post-traumatic stress disorder: highlights of epigenetics and epigenomics
Exposure to trauma is one of the most important and prevalent risk factors for mental and
physical ill-health. Excessive or prolonged stress exposure increases the risk of a wide …
physical ill-health. Excessive or prolonged stress exposure increases the risk of a wide …
[HTML][HTML] Overcoming resistance to selective serotonin reuptake inhibitors: targeting serotonin, serotonin-1A receptors and adult neuroplasticity
F Vahid-Ansari, M Zhang, A Zahrai… - Frontiers in …, 2019 - frontiersin.org
Major depressive disorder (MDD) is the most prevalent mental illness contributing to global
disease burden. Selective serotonin (5-HT) reuptake inhibitors (SSRIs) are the first-line …
disease burden. Selective serotonin (5-HT) reuptake inhibitors (SSRIs) are the first-line …
[HTML][HTML] Central serotonin modulates neural responses to virtual violent actions in emotion regulation networks
D Wolf, M Klasen, P Eisner, FD Zepf… - Brain structure and …, 2018 - Springer
Disruptions in the cortico-limbic emotion regulation networks have been linked to
depression, anxiety, impulsivity, and aggression. Altered transmission of the central nervous …
depression, anxiety, impulsivity, and aggression. Altered transmission of the central nervous …
Common and differential neural mechanisms underlying mood disorders
Background Despite homogenous clinical presentations between bipolar and unipolar
disorders, there are distinct neurobiological differences. Chronicity of illness may be a factor …
disorders, there are distinct neurobiological differences. Chronicity of illness may be a factor …
The use of pharmacogenetic testing in patients with schizophrenia or bipolar disorder: A systematic review
M Routhieaux, J Keels, EE Tillery - Mental Health Clinician, 2018 - meridian.allenpress.com
Introduction: Pharmacogenetic testing may assist in identifying an individual's risk of
developing a mental illness as well as predict an individual's response to treatment. The …
developing a mental illness as well as predict an individual's response to treatment. The …
Depressive-like state sensitizes 5-HT1A and 5-HT1B auto-receptors in the dorsal raphe nucleus sub-system
X Li, X Sun, J Sun, Y Zu, S Zhao, X Sun, L Li… - Behavioural Brain …, 2020 - Elsevier
Dorsal raphe (DR) and median raphe (MR) 5-HT neurons are two distinct sub-systems
known to be regulated by 5-HT 1A and 5-HT 1B auto-receptors. Whether the auto-receptors …
known to be regulated by 5-HT 1A and 5-HT 1B auto-receptors. Whether the auto-receptors …
An electrophysiological model of major depression: Relevance to clinical subtyping and pharmacological management
IH Cerda, PJ Fitzgerald - Psychiatry Research, 2021 - Elsevier
We present a neurochemical model of unipolar major depressive disorder that makes
predictions for optimizing pharmacological treatment of this debilitating neuropsychiatric …
predictions for optimizing pharmacological treatment of this debilitating neuropsychiatric …
Sublethal effects of neuroactive pharmaceuticals in developing zebrafish (Danio rerio), an aquatic vertebrate model organism
I Huang - 2019 - search.proquest.com
Neuroactive pharmaceuticals (NPs) are commonly detected in the environment worldwide,
however typically at low concentrations. Despite this low level of contamination, NPs are …
however typically at low concentrations. Despite this low level of contamination, NPs are …
[HTML][HTML] Asperger's, meltdowns, and the feel-good neurotransmitter
LPY Plan, PY Plan - mendability.com
Serotonin is a neurotransmitter (ie brain chemical) involved in the regulation of a variety of
crucial functions including mood, sleep, memory, and appetite (Brady, Siegel, Albers, & …
crucial functions including mood, sleep, memory, and appetite (Brady, Siegel, Albers, & …