[HTML][HTML] Extracellular vesicles: biomarkers, therapeutics, and vehicles in the visual system
Y van der Merwe, MB Steketee - Current Ophthalmology Reports, 2017 - Springer
Purpose We discuss recent advances in extracellular vesicle (EV) technology as biomarkers,
therapeutics, and drug delivery vehicles in the visual system with an emphasis on the retina…
therapeutics, and drug delivery vehicles in the visual system with an emphasis on the retina…
Nanoparticle-mediated signaling endosome localization regulates growth cone motility and neurite growth
MB Steketee, SN Moysidis, XL Jin… - Proceedings of the …, 2011 - National Acad Sciences
Understanding neurite growth regulation remains a seminal problem in neurobiology.
During development and regeneration, neurite growth is modulated by neurotrophin-activated …
During development and regeneration, neurite growth is modulated by neurotrophin-activated …
Three functionally distinct adhesions in filopodia: shaft adhesions control lamellar extension
MB Steketee, KW Tosney - Journal of Neuroscience, 2002 - Soc Neuroscience
In this study, adhesions on individual filopodial shafts were shown to control veil (lamellar)
advance and to be modulated by guidance cues. Adhesions were detected in individual …
advance and to be modulated by guidance cues. Adhesions were detected in individual …
[HTML][HTML] Matrix-bound nanovesicles prevent ischemia-induced retinal ganglion cell axon degeneration and death and preserve visual function
…, IP Conner, VLN Fu, SF Badylak, MB Steketee - Scientific reports, 2019 - nature.com
Injury to retinal ganglion cells (RGC), central nervous system neurons that relay visual
information to the brain, often leads to RGC axon degeneration and permanently lost visual …
information to the brain, often leads to RGC axon degeneration and permanently lost visual …
[HTML][HTML] Mitochondrial dynamics regulate growth cone motility, guidance, and neurite growth rate in perinatal retinal ganglion cells in vitro
MB Steketee, SN Moysidis… - … & visual science, 2012 - iovs.arvojournals.org
Purpose.: Retinal ganglion cell (RGC) death and failed axonal regeneration after trauma or
disease, including glaucomatous and mitochondrial optic neuropathies, are linked …
disease, including glaucomatous and mitochondrial optic neuropathies, are linked …
[HTML][HTML] Regulation of intrinsic axon growth ability at retinal ganglion cell growth cones
MB Steketee, C Oboudiyat, R Daneman… - … & visual science, 2014 - iovs.arvojournals.org
Purpose.: Mammalian central nervous system neurons fail to regenerate after injury or disease,
in part due to a progressive loss in intrinsic axon growth ability after birth. Whether lost …
in part due to a progressive loss in intrinsic axon growth ability after birth. Whether lost …
Promoting filopodial elongation in neurons by membrane-bound magnetic nanoparticles
W Pita-Thomas, MB Steketee, SN Moysidis… - … , Biology and Medicine, 2015 - Elsevier
… Steketee PhD a c , Stavros N. Moysidis MD a , Kinjal Thakor a , Blake Hampton BS a ,
Jeffrey L. Goldberg MD PhD a d … MB Steketee, KW Tosney … MB Steketee, KW Tosney …
Jeffrey L. Goldberg MD PhD a d … MB Steketee, KW Tosney … MB Steketee, KW Tosney …
Developing extracellular matrix technology to treat retinal or optic nerve injury
T Ren, Y van der Merwe, MB Steketee - ENeuro, 2015 - eneuro.org
Adult mammalian CNS neurons often degenerate after injury, leading to lost neurologic
functions. In the visual system, retinal or optic nerve injury often leads to retinal ganglion cell …
functions. In the visual system, retinal or optic nerve injury often leads to retinal ganglion cell …
[HTML][HTML] Fetal extracellular matrix nerve wraps locally improve peripheral nerve remodeling after complete transection and direct repair in rat
…, SF Badylak, KM Washington, MB Steketee - Scientific reports, 2018 - nature.com
In peripheral nerve (PN) injuries requiring surgical repair, as in PN transection, cellular and
ECM remodeling at PN epineurial repair sites is hypothesized to reduce PN functional …
ECM remodeling at PN epineurial repair sites is hypothesized to reduce PN functional …
[HTML][HTML] Matrix bound vesicles and miRNA cargoes are bioactive factors within extracellular matrix bioscaffolds
…, AE Faust, MB Steketee - Neural regeneration …, 2017 - journals.lww.com
… Ren T, van der Merwe Y, Steketee MB. Developing extracellular matrix technology to treat
… van der Merwe Y, Steketee MB. Immunomodulatory approaches to CNS injury: extracellular …
… van der Merwe Y, Steketee MB. Immunomodulatory approaches to CNS injury: extracellular …