[HTML][HTML] Comprehensive behavioral analysis of mice deficient in Rapgef2 and Rapgef6, a subfamily of guanine nucleotide exchange factors for Rap small GTPases …
… Mice used in this study had been backcrossed over 11 times to the C57BL/6 J strain.
Rapgef2-cKO (Rapgef2 flox/flox ;Emx1 cre/+ ) mice were prepared by mating Rapgef2 flox/flox mice …
Rapgef2-cKO (Rapgef2 flox/flox ;Emx1 cre/+ ) mice were prepared by mating Rapgef2 flox/flox mice …
Crucial role of Rapgef2 and Rapgef6, a family of guanine nucleotide exchange factors for Rap1 small GTPase, in formation of apical surface adherens junctions and …
K Maeta, H Edamatsu, K Nishihara, J Ikutomo… - Eneuro, 2016 - eneuro.org
Cerebral neocortex development in mammals requires highly orchestrated events involving
proliferation, differentiation, and migration of neural progenitors and neurons. Rapgef2 and …
proliferation, differentiation, and migration of neural progenitors and neurons. Rapgef2 and …
Gait abnormality predicts falls in women after total hip arthroplasty
Background Patients who undergo total hip arthroplasty (THA) have an increased risk of falls
during the first year postoperatively. However, risk factors for falls after THA remain unclear. …
during the first year postoperatively. However, risk factors for falls after THA remain unclear. …
Fear of falling during activities of daily living after total hip arthroplasty in Japanese women: a cross-sectional study
Objectives To investigate the prevalence of fear of falling, and identify factors associated with
fear of falling during activities of daily living after total hip arthroplasty (THA). Design Cross-…
fear of falling during activities of daily living after total hip arthroplasty (THA). Design Cross-…
Effect of streptozotocin-induced diabetes on motor representations in the motor cortex and corticospinal tract in rats
K Muramatsu, M Ikutomo, T Tamaki, S Shimo, M Niwa - Brain research, 2018 - Elsevier
… I–J: Comparisons of the control and diabetic animals for average number (I) and mean cross…
I–J: Comparisons of the control and diabetic animals for average number (I) and mean cross-…
I–J: Comparisons of the control and diabetic animals for average number (I) and mean cross-…
Motor skills training-induced activation of descending pathways mediating cortical command to hindlimb motoneurons in experimental diabetic rats
K Muramatsu, N Niimi, M Ikutomo, S Shimo… - Experimental …, 2023 - Elsevier
Diabetes disrupts the corticospinal tract (CST) system components that control hindlimb and
trunk movement, resulting in weakness of the lower extremities. However, there is no …
trunk movement, resulting in weakness of the lower extremities. However, there is no …
Midkine-deficient mice delayed degeneration and regeneration after skeletal muscle injury
M Ikutomo, H Sakakima, F Matsuda, Y Yoshida - Acta histochemica, 2014 - Elsevier
Midkine (MK), a heparin-binding growth factor, was previously found to be expressed in the
rat myotube-forming stage. We investigated MK gene-deficient (Mdk −/− ) mice in terms of …
rat myotube-forming stage. We investigated MK gene-deficient (Mdk −/− ) mice in terms of …
Effect of streptozotocin-induced diabetes on motoneurons and muscle spindles in rats
K Muramatsu, M Niwa, T Tamaki, M Ikutomo… - Neuroscience …, 2017 - Elsevier
This study examined the alterations in the number and size of motoneurons innervating the
medial gastrocnemius (MG) and biceps femoris (BF) motor nuclei in diabetic rats (12 or 22 …
medial gastrocnemius (MG) and biceps femoris (BF) motor nuclei in diabetic rats (12 or 22 …
Incidence and circumstances of falls in women before and after total hip arthroplasty: a prospective cohort study
Background We investigated the incidence and circumstances related to falls in patients
before and after total hip arthroplasty (THA), and compared them with those in an age-matched …
before and after total hip arthroplasty (THA), and compared them with those in an age-matched …
Asymmetrical loading during sit-to-stand movement in patients 1 year after total hip arthroplasty
N Miura, K Tagomori, H Ikutomo, N Nakagawa… - Clinical …, 2018 - Elsevier
Background Asymmetrical loading during functional performance can occur after total hip
arthroplasty. We hypothesized that during sit-to-stand movements, the loading of the limbs of …
arthroplasty. We hypothesized that during sit-to-stand movements, the loading of the limbs of …