User profiles for J. Hayes

John D Hayes

Scotland
Verified email at dundee.ac.uk
Cited by 52643

Glutathione transferases

JD Hayes, JU Flanagan… - Annu. Rev. Pharmacol …, 2005 - annualreviews.org
▪ Abstract This review describes the three mammalian glutathione transferase (GST) families,
namely cytosolic, mitochondrial, and microsomal GST, the latter now designated MAPEG. …

The glut athione S-transferase supergene family: regulation of GST and the contribution of the lsoenzymes to cancer chemoprotection and drug resistance part II

JD Hayes, DJ Pulford - Critical reviews in biochemistry and …, 1995 - Taylor & Francis
The glutathione S-transferases (GST) represent a major group of detoxification enzymes. All
eukaryotic species possess multiple cytosolic and membrane-bound GST isoenzymes, each …

[PDF][PDF] Oxidative stress in cancer

JD Hayes, AT Dinkova-Kostova, KD Tew - Cancer cell, 2020 - cell.com
Contingent upon concentration, reactive oxygen species (ROS) influence cancer evolution
in apparently contradictory ways, either initiating/stimulating tumorigenesis and supporting …

Direct detection of bacterial biofilms on the middle-ear mucosa of children with chronic otitis media

…, FZ Hu, A Gieseke, L Nistico, D Nguyen, J Hayes… - Jama, 2006 - jamanetwork.com
ContextChronic otitis media (OM) is a common pediatric infectious disease. Previous studies
demonstrating that metabolically active bacteria exist in culture-negative pediatric middle-…

[HTML][HTML] Mutagenesis identifies new signals for β-amyloid precursor protein endocytosis, turnover, and the generation of secreted fragments, including Aβ42

RG Perez, S Soriano, JD Hayes, B Ostaszewski… - Journal of Biological …, 1999 - ASBMB
It has long been assumed that the C-terminal motif, NPXY, is the internalization signal for β-amyloid
precursor protein (APP) and that the NPXY tyrosine (Tyr 743 by APP751 numbering, …

Mucosal biofilm formation on middle-ear mucosa in the chinchilla model of otitis media

GD Ehrlich, R Veeh, X Wang, JW Costerton, JD Hayes… - Jama, 2002 - jamanetwork.com
ContextChronic otitis media with effusion (OME) has long been considered to be a sterile
inflammatory process. The previous application of molecular diagnostic technologies to OME …

Comparative Genomic Analyses of Seventeen Streptococcus pneumoniae Strains: Insights into the Pneumococcal Supragenome

…, S Yu, E Powell, R Keefe, NE Ehrlich, K Shen, J Hayes… - 2007 - Am Soc Microbiol
The distributed-genome hypothesis (DGH) states that pathogenic bacteria possess a
supragenome that is much larger than the genome of any single bacterium and that these …

[HTML][HTML] Characterization and modeling of the Haemophilus influenzae core and supragenomes based on the complete genomic sequences of Rd and 12 clinical …

JS Hogg, FZ Hu, B Janto, R Boissy, J Hayes, R Keefe… - Genome biology, 2007 - Springer
Background The distributed genome hypothesis (DGH) posits that chronic bacterial pathogens
utilize polyclonal infection and reassortment of genic characters to ensure persistence in …

The sloan digital sky survey: Technical summary

…, M Haldeman, FH Harris, J Hayes… - The Astronomical …, 2000 - iopscience.iop.org
The Sloan Digital Sky Survey (SDSS) will provide the data to support detailed investigations
of the distribution of luminous and nonluminous matter in the universe: a photometrically …

[BOOK][B] The complete problem solver

JR Hayes - 2013 - taylorfrancis.com
… Professor Hayes provides students and professionals with practical, tested methods of
defining, representing, and solving problems. Each discussion of the important aspects of human …