Lentiviral-mediated silencing of SOD1 through RNA interference retards disease onset and progression in a mouse model of ALS
…, JC Bensadoun, S Guillot, G Haase, J Szulc… - Nature medicine, 2005 - nature.com
… densitometric analysis using the US National Institutes of Health Image J software. … We
specially thank J. Iovanna for biosafety level 2 laboratory accommodation at Marseille. This work …
specially thank J. Iovanna for biosafety level 2 laboratory accommodation at Marseille. This work …
Self-inactivating lentiviral vectors with enhanced transgene expression as potential gene transfer system in Parkinson's disease
N Deglon, JL Tseng, JC Bensadoun, AD Zurn… - Human gene …, 2000 - liebertpub.com
Glial cell line-derived neurotrophic factor (GDNF) is able to protect dopaminergic neurons
against various insults and constitutes therefore a promising candidate for the treatment of …
against various insults and constitutes therefore a promising candidate for the treatment of …
Demonstration of cortical recording using novel flexible polymer neural probes
…, M Boers, A Maillard, P Colin, JC Bensadoun… - Sensors and Actuators A …, 2008 - Elsevier
We present the fabrication, characterization, use in cortical recording and histological
results of a flexible implantable neural probe. The microfabricated device is implemented in …
results of a flexible implantable neural probe. The microfabricated device is implemented in …
Lentiviral vectors as a gene delivery system in the mouse midbrain: cellular and behavioral improvements in a 6-OHDA model of Parkinson's disease using GDNF
JC Bensadoun, N Déglon, JL Tseng, JL Ridet… - Experimental …, 2000 - Elsevier
Local delivery of therapeutic molecules represents one of the limiting factors for the treatment
of neurodegenerative disorders. In vivo gene transfer using viral vectors constitutes a …
of neurodegenerative disorders. In vivo gene transfer using viral vectors constitutes a …
Nigrostriatal overabundance of α-synuclein leads to decreased vesicle density and deficits in dopamine release that correlate with reduced motor activity
…, OM El-Agnaf, M Cantoni, JC Bensadoun… - Acta …, 2012 - Springer
α-Synuclein (α-syn) is a presynaptic protein present at most nerve terminals, but its function
remains largely unknown. The familial forms of Parkinson’s disease associated with …
remains largely unknown. The familial forms of Parkinson’s disease associated with …
In Vivo Electrical Impedance Spectroscopy of Tissue Reaction to Microelectrode Arrays
A Mercanzini, P Colin, JC Bensadoun… - IEEE Transactions …, 2009 - ieeexplore.ieee.org
The goal of this experiment was to determine the electrical properties of the tissue reaction
to implanted microelectrode arrays. We describe a new method of analyzing electrical …
to implanted microelectrode arrays. We describe a new method of analyzing electrical …
[PDF][PDF] KAP1-mediated epigenetic repression in the forebrain modulates behavioral vulnerability to stress
…, R Bisaz, AC Groner, V Busskamp, JC Bensadoun… - Neuron, 2008 - cell.com
KAP1 is an essential cofactor of KRAB-zinc finger proteins, a family of vertebrate-specific
epigenetic repressors of largely unknown functions encoded in the hundreds by the mouse and …
epigenetic repressors of largely unknown functions encoded in the hundreds by the mouse and …
In vivo gene therapy of metachromatic leukodystrophy by lentiviral vectors: correction of neuropathology and protection against learning impairments in affected mice
A Consiglio, A Quattrini, S Martino, JC Bensadoun… - Nature medicine, 2001 - nature.com
Metachromatic leukodystrophy (MLD) is a lipidosis caused by deficiency of arylsulfatase A (ARSA).
Although the genetics of MLD are known, its pathophysiology is not understood. The …
Although the genetics of MLD are known, its pathophysiology is not understood. The …
Common oral complications of head and neck cancer radiation therapy: mucositis, infections, saliva change, fibrosis, sensory dysfunctions, dental caries, periodontal …
HY Sroussi, JB Epstein, RJ Bensadoun… - Cancer …, 2017 - Wiley Online Library
Patients undergoing radiation therapy for the head and neck are susceptible to a significant
and often abrupt deterioration in their oral health. The oral morbidities of radiation therapy …
and often abrupt deterioration in their oral health. The oral morbidities of radiation therapy …
Oral complications of cancer and cancer therapy: from cancer treatment to survivorship
JB Epstein, J Thariat, RJ Bensadoun… - CA: a cancer journal …, 2012 - Wiley Online Library
… Rene-Jean Bensadoun MD, HDR … CA Cancer J Clin 2012. © 2012 American Cancer
Society. … PUVA: psoralen at dose of 10 mg or 20 mg one hour before UV light (0.5 J/cm 2 ) …
Society. … PUVA: psoralen at dose of 10 mg or 20 mg one hour before UV light (0.5 J/cm 2 ) …