User profiles for A. S. Lee
Allen S. LeeProfessor Emeritus of Information Systems, Virginia Commonwealth University Verified email at alum.mit.edu Cited by 15723 |
Stress induction of GRP78/BiP and its role in cancer
J Li, AS Lee - Current molecular medicine, 2006 - ingentaconnect.com
… may exist as a cell surface transmembrane protein as well. Recently, it has been reported
that MTJ-1, which is itself a transmembrane protein, associates with GRP78 in the ER as a co-…
that MTJ-1, which is itself a transmembrane protein, associates with GRP78 in the ER as a co-…
GRP78 induction in cancer: therapeutic and prognostic implications
AS Lee - Cancer research, 2007 - AACR
… Autoantibody levels against GRP78 in patient serum, as well as expression levels of GRP78
in biopsies, may represent novel biomarkers in stratifying patients for tumor behavior and …
in biopsies, may represent novel biomarkers in stratifying patients for tumor behavior and …
[HTML][HTML] Methicillin-resistant Staphylococcus aureus
AS Lee, H De Lencastre, J Garau… - Nature reviews Disease …, 2018 - nature.com
… aureus has the remarkable ability to acquire resistance to any antibiotic 7 , which has
major implications for current as well as future treatment options for this pathogen. …
major implications for current as well as future treatment options for this pathogen. …
A scientific methodology for MIS case studies
AS Lee - MIS quarterly, 1989 - JSTOR
… of the system will reduce resistance as long as the conditions which gave rise to it persist.
[The prediction is that there will be resistance as long as there are] mismatches between the …
[The prediction is that there will be resistance as long as there are] mismatches between the …
[HTML][HTML] Endoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53
J Li, B Lee, AS Lee - Journal of Biological Chemistry, 2006 - ASBMB
… /EBP homologous protein (CHOP) and caspase-12, as their activation is intact in p53 -/- MEFs.
In … Reversibly, overexpression of NOXA or PUMA induces apoptosis as evidenced by the …
In … Reversibly, overexpression of NOXA or PUMA induces apoptosis as evidenced by the …
Diet and the evolution of human amylase gene copy number variation
… as in our study. For the Yakut aCGH experiments, we used the same reference DNA sample
(NA10851) as … because microsatellite loci are usually multiallelic (as is the AMY1 locus). We …
(NA10851) as … because microsatellite loci are usually multiallelic (as is the AMY1 locus). We …
Integrating positivist and interpretive approaches to organizational research
AS Lee - Organization science, 1991 - pubsonline.informs.org
The interpretive approach to organizational research has been gaining increasing attention
as a legitimate alternative to the more traditional positivist approach. The organizational …
as a legitimate alternative to the more traditional positivist approach. The organizational …
[HTML][HTML] The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells
… formation induced by ER stress as well as by nutrition starvation was inhibited. GRP78 …
Thus, these studies uncover 3-MA as an inhibitor of UPR activation and establish GRP78 as …
Thus, these studies uncover 3-MA as an inhibitor of UPR activation and establish GRP78 as …
Generalizing generalizability in information systems research
AS Lee, RL Baskerville - Information systems research, 2003 - pubsonline.informs.org
Generalizability is a major concern to those who do, and use, research. Statistical, sampling-based
generalizability is well known, but methodologists have long been aware of …
generalizability is well known, but methodologists have long been aware of …
Development and validation of the voice handicap index‐10
CA Rosen, AS Lee, J Osborne, T Zullo… - The …, 2004 - Wiley Online Library
… The goal of the present study was to explore and possibly to develop a shortened VHI as
a vocal function assessment tool both for initial evaluation and for longitudinal assessment of …
a vocal function assessment tool both for initial evaluation and for longitudinal assessment of …