User profiles for A. G. Otopalik

Adriane G. Otopalik

Incoming Group Leader, Janelia Research Campus, HHMI
Verified email at janelia.hhmi.org
Cited by 428

Robust circuit rhythms in small circuits arise from variable circuit components and mechanisms

E Marder, ML Goeritz, AG Otopalik - Current opinion in neurobiology, 2015 - Elsevier
Highlights • Analysis of small oscillatory circuits reveals variability in system parameters. •
Circuits with different parameter sets can be robust to moderate perturbations. • Circuits with …

When complex neuronal structures may not matter

AG Otopalik, AC Sutton, M Banghart, E Marder - Elife, 2017 - elifesciences.org
10.7554/eLife.23508.001 Much work has explored animal-to-animal variability and
compensation in ion channel expression. Yet, little is known regarding the physiological …

Sloppy morphological tuning in identified neurons of the crustacean stomatogastric ganglion

AG Otopalik, ML Goeritz, AC Sutton, T Brookings… - Elife, 2017 - elifesciences.org
10.7554/eLife.22352.001 Neuronal physiology depends on a neuron’s ion channel
composition and unique morphology. Variable ion channel compositions can produce similar …

Molecular profiling of single neurons of known identity in two ganglia from the crab Cancer borealis

AJ Northcutt, DR Kick, AG Otopalik… - Proceedings of the …, 2019 - National Acad Sciences
Understanding circuit organization depends on identification of cell types. Recent advances
in transcriptional profiling methods have enabled classification of cell types by their gene …

Neuronal morphologies built for reliable physiology in a rhythmic motor circuit

AG Otopalik, J Pipkin, E Marder - Elife, 2019 - elifesciences.org
10.7554/eLife.41728.001 It is often assumed that highly-branched neuronal structures perform
compartmentalized computations. However, previously we showed that the Gastric Mill (…

[HTML][HTML] Quantitative reevaluation of the effects of short-and long-term removal of descending modulatory inputs on the pyloric rhythm of the crab, Cancer borealis

AW Hamood, SA Haddad, AG Otopalik, P Rosenbaum… - Eneuro, 2015 - eneuro.org
The crustacean stomatogastric ganglion (STG) receives descending neuromodulatory
inputs from three anterior ganglia: the paired commissural ganglia (CoGs), and the single …

[HTML][HTML] Innexin expression in electrically coupled motor circuits

AG Otopalik, B Lane, DJ Schulz, E Marder - Neuroscience letters, 2019 - Elsevier
The many roles of innexins, the molecules that form gap junctions in invertebrates, have
been explored in numerous species. Here, we present a summary of innexin expression and …

Differential uptake of MRI contrast agents indicates charge-selective blood-brain interface in the crayfish

AG Otopalik, J Shin, BS Beltz, DC Sandeman… - Cell and tissue …, 2012 - Springer
This study provides a new perspective on the long-standing problem of the nature of the
decapod crustacean blood-brain interface. Previous studies of crustacean blood-brain interface …

Molecular Profiling to Infer Neuronal Cell Identity: Lessons from small ganglia of the Crab Cancer borealis

AJ Northcutt, DR Kick, AG Otopalik, BM Goetz… - bioRxiv, 2019 - biorxiv.org
Understanding circuit organization depends on identification of cell types. Recent advances
in transcriptional profiling methods have enabled classification of cell types by their gene …

Single-Neuron Gene Expression Analysis Using the Maxwell® 16 LEV System in the Neural Systems and Behavior Course

RM Harris, AG Otopalik, CJ Smith, D Bucher… - bioRxiv, 2017 - biorxiv.org
Gene expression analysis from single cells has become increasingly prominent across
biological disciplines; thus, it is important to train students in these approaches. Here, we present …