Positive Regulatory Genes in Peripheral Axon Regeneration and Functional Recovery Following Injury

Peripheral nervous system (PNS) is well known to exhibit the capacity of axon regeneration and functional recovery after injury. However, such regeneration and functional recovery are often limited. A plethora of studies have identified numerous factors that positively regulate and support the process of peripheral axon regeneration and functional recovery. Here, the main aim of this review article is to summarise and provide updated summary of the In-vivo knock-out (KO) studies that have shown the positive regulatory effects of various genes or proteins to enhance axon regeneration and functional recovery following PNS injury.