Abstract
In rats with hereditary hypothalamic diabetes insipidus (Brattleboro rats) the gene for the vasopressin precursor lacks a single G residue in the protein-coding region. The mutation gives rise to an open reading frame predicting a hormone precursor having a different C-terminus.
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Schmale, H., Richter, D. Single base deletion in the vasopressin gene is the cause of diabetes insipidus in Brattleboro rats. Nature 308, 705–709 (1984). https://doi.org/10.1038/308705a0
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DOI: https://doi.org/10.1038/308705a0
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