Long-lasting recovery of locomotor function in chronic spinal rat following chronic combined pharmacological stimulation of serotonergic receptors with 8-OHDPAT and quipazine
Section snippets
Acknowledgments
This work was funded by grants from the Christopher Reeve Paralysis Foundation (CRPF) and from the Institut de Recherche sur la Moelle et l’Encéphale (IRME). The authors warmly thank P. Drapeau and Pr. S. Rossignol at the CRSN, University of Montréal (Québec) for providing their homemade and powerful, software Expresso. We are grateful to K. Todd for his valuable comments. Myriam Antri received a fellowship from IRME.
References (32)
- et al.
Initiation and modulation of the locomotor pattern in the adult chronic spinal cat by noradrenergic, serotonergic and dopaminergic drugs
Brain Res.
(1991) - et al.
Effects of 5,7-dihydroxytryptamine on serotonin1 and serotonin2 receptors throughout the rat central nervous system using quantitative autoradiography
Brain Res.
(1987) - et al.
Autoreceptors remain functional after prolonged treatment with a serotonin reuptake inhibitor
Brain Res.
(1999) - et al.
Identification of 5-hydroxytryptamine binding site subtypes in rat spinal cord
Brain Res.
(1987) - et al.
The cellular localization of 5-HT2A receptors in the spinal cord and spinal ganglia of the adult rat
Brain Res.
(1998) - et al.
Autoradiographic mapping of 5-HT1, 5-HT1A, 5-HT1B and 5-HT2 receptors in the rat spinal cord
Brain Res.
(1991) - et al.
Locomotor recovery in adult spinal rats: long term pharmacological treatment or transplantation of embryonic neurons?
Prog. Brain Res.
(2002) - et al.
The 5HT1A receptor agonist, 8-OH-DPAT, protects neurons and reduces astroglial reaction after ischemic damage caused by cortical devascularization
Brain Res.
(2004) - et al.
The role of serotonin in reflex modulation and locomotor rhythm production in the mammalian spinal cord
Brain Res. Bull.
(2000) - et al.
5-HT1A receptors are involved in short- and long-term processes responsible for 5-HT-induced locomotor function recovery in chronic spinal rat
Eur. J. Neurosci.
(2003)
Locomotor recovery in the chronic spinal rat: effects of long-term treatment with a 5-HT2 agonist
Eur. J. Neurosci.
(2002)
Neural transplantation in adult rats
Activation of the central pattern generators for locomotion by serotonin and excitatory amino acids in neonatal rat
J. Physiol.
(1992)
Cellular and subcellular distribution of the serotonin 5-HT2A receptor in the central nervous system of adult rat
J. Comp. Neurol.
(1999)
5-HT5A receptor localization in the rat spinal cord suggests a role in nociception and control of pelvic floor musculature
J. Comp. Neurol.
(2004)
The 5-HT2A receptor is widely distributed in the rat spinal cord and mainly localized at the plasma membrane of postsynaptic neurons
J. Comp. Neurol.
(2004)
Cited by (0)
Copyright © 2005 Elsevier Ireland Ltd. All rights reserved.