Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Volume 1822, Issue 3, March 2012, Pages 386-400
ReviewDiffusion tensor imaging of cerebral white matter integrity in cognitive aging☆
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Highlights
► We review diffusion tensor imaging (DTI) of white matter (WM) integrity in aging. ► Even without disease, age-related decline occurs in both cognition and WM integrity. ► Age-related decline in WM integrity interrupts communication among brain networks. ► Disconnection of brain network may contribute to normal cognitive decline with age.
Keywords
Magnetic resonance imaging
Brain
Behavior
Adult development
Neuroaxonal damage
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This article is part of a Special Issue entitled: Imaging Brain Aging and Neurodegenerative disease.
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