Progress in Neuro-Psychopharmacology and Biological Psychiatry
The psychopharmacology-molecular biology interface: exploring the behavioural roles of dopamine receptor subtypes using targeted gene deletion (‘knockout’)
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Cited by (57)
Dopamine D3 receptor knock-out mice exhibit increased behavioral sensitivity to the anxiolytic drug diazepam
2011, European NeuropsychopharmacologyBehavioral pharmacology of orofacial movement disorders
2011, International Review of NeurobiologyRegulation Of Orofacial Movement: Dopamine Receptor Mechanisms And Mutant Models
2011, International Review of NeurobiologyCitation Excerpt :This suggests a broader concept of D1 and D5 receptor function than simply motoric, to involve interactions with those psychomotor processes that modulate orofacial function over time (Waddington et al., 2005). As indicated in Tables VII and IX, these profiles are reinforced by essential abolition of D1-like agonist stimulation of orofacial movements in D1 KO; enhancement of D2-like agonist effects in D1 KO further indicates disruption to D1:D2-like interactions (Waddington et al., 1994, 2001), such that D1 receptors oppose the actions of D2-like receptors with respect to the inhibition of jaw movements and facilitation of head movements; D5 receptors appear to play no role in these effects of D1-like and D2-like agonists. However, two paradoxes require explanation.
Pharmacology of signaling induced by dopamine D<inf>1</inf>-like receptor activation
2010, Pharmacology and TherapeuticsDopamine receptor subtypes and orofacial movement topographies: studies with mutant models
2010, Journal of Oral Biosciences