Table 2:

Metanicotine

TrpB	EC₅₀ (μM)	n_H	I_max (μA)	Fold shift	N
Trp	0.64 ± 0.02	1.3 ± 0.0	0.08–0.89	1	13
F₁Trp	0.79 ± 0.02	1.4 ± 0.0	0.12–0.80	1.2	16
F₂Trp	3.6 ± 0.1	1.5 ± 0.1	0.15–0.56	5.6	14
F₃Trp	13 ± 1	1.6 ± 0.1	0.07–0.30	20	12
F₄Trp	16 ± 2	1.3 ± 0.1	0.03–0.11	25	12
TyrA	EC₅₀ (μM)	n_H	I_max (μA)	Fold shift	N
Phe	19 ± 5	1.1 ± 0.2	0.02–0.16	1	7
F₃Phe	17 ± 2	1.3 ± 0.1	0.01–0.03	0.9	6
TyrC2	EC₅₀ (μM)	n_H	I_max (μA)	Fold shift	N
Phe	0.41 ± 0.03	1.2 ± 0.07	0.06–2.78	1	17
F₁Phe	0.86 ± 0.06	1.2 ± 0.08	0.04–0.07	2.1	11
F₂Phe	11 ± 1	0.6 ± 0.1	0.03–0.13	27	8
F₃Phe	21 ± 1	1.4 ± 0.2	0.04–0.24	51	12