1. Authors | 2. Age | 3. Change | 4. Magnitude of change | 5. Calculated effect size | 6. Grouping unit | 7. Blinding | 8. Power analysis | 9. Size parameter | 10. Sex/no. of animals (WT, G93A) |
---|---|---|---|---|---|---|---|---|---|
Pullen and Athanasiou (2009) | P42P70P156 | NCIncreaseIncrease | N/A25%56% | N/A0.711.42 | By bouton | Not reported | Not reported | Appositional length | M2 |
Herron and Miles (2012) | P8P30P120P140 | NCIncreaseIncreaseIncrease | N/A7%14%17% | Inadequate information1 | Byanimal | Blindingincluded | Not reported | Appositional length (Feret’s diameter) | M (25 mice total for all time points and groups)3 |
Saxena et al. (2013) | P37 | Increase | 100% | Inadequate information1 | By bouton | Not reported | Not reported | Volume | M (3, 3) |
Milan et al. (2015) | P10P21P40P75P100 | DecreaseIncreaseNCNCDecrease | 9%7%N/AN/A5% | 0.150.17N/AN/A0.43 | Bycell | Blindingincluded | Not reported | Area | M (6, 6)M (7, 6)M (8, 6)M (6, 7)M (5, 8) |
This article | P10P30P90P120+ | NCNCNCNC | N/A | N/AN/AN/AN/A | Bycell | Blindingincluded | Included | Largest cross-sectional area | M (3, 3)M (4, 4)M (3, 3)M (3, 3) |
1, Authors; 2, age of G93A mouse studied; 3, whether C-bouton size increases, decreases, or there was no change were reported for each age studied; 4, magnitude of change; 5, calculated effect size, if possible; 6, the sampling strategy (grouping unit) used; 7, the reported blinding status, if reported; and 8, the power analysis, if reported. M, Male; N/A, not available; NC, no change.
↵1Inadequate information. SD values or sample size (n) data were not included in the published work, making the calculation of effect size impossible.
↵2No information on animal number was provided.
↵3Information on each time point was not provided. Female data not included in the table comparison.