Functional annotation chart of selected lithium-responsive genes analyzed by DAVID.
| Enriched Gene Ontology (GO) annotation terms | GO ID | p-valuea | Fold enrichment |
|---|---|---|---|
| Cellular amino acid biosynthetic process | 0008652 | 5.1 × 10−8 | 21.7 |
| Carboxylic/organic acid biosynthetic process | 0046394/0016053b | 8.6 × 10−8 | 12.3 |
| Amine biosynthetic process | 0009309 | 1.0 × 10−7 | 15.0 |
| Cofactor binding | 0048037 | 5.5 × 10−7 | 5.4 |
| Oxidation-reduction process | 0055114 | 1.8 × 10−6 | 3.0 |
| Lipid particle | 0005811 | 2.4 × 10−6 | 4.9 |
| L-serine biosynthetic process | 0006564 | 7.7 × 10−6 | 78.6 |
| Hexose metabolic process | 0019318 | 1.0 × 10−5 | 8.3 |
| Aspartate family amino acid metabolic process | 0009066 | 1.6 × 10−5 | 30.2 |
| L-serine metabolic process | 0006563 | 1.9 × 10−5 | 62,9 |
| Monosaccharide metabolic process | 0005996 | 2.7 × 10−5 | 7.3 |
| Mitochondrion | 0005739 | 2.8 × 10−5 | 2.9 |
| Cellular nitrogen compound biosynthetic process | 0044271 | 3.3 × 10−5 | 4.4 |
| Serine family amino acid metabolic process | 0009069 | 3.8 × 10−5 | 24.6 |
| IMP biosynthetic/metabolic process | 0006188/0046040c | 6.5 × 10−5 | 44.9 |
| Serine family amino acid biosynthetic process | 0009070 | 6.5 × 10−5 | 44.9 |
| Transaminase activity | 0008483 | 7.4 × 10−5 | 20.8 |
↵ap-value for a modified Fisher exact test (EASE score). b,cThe identical genes are assigned to these terms for the Drosophila genome.