Table 1.

Intrinsic electrophysiological properties of three groups of neurons recorded: pyramidal neurons in L6, FS interneurons in L5, and nFS interneurons in L5.

RMP (mV)Input resistance (MΩ)Spike amplitude (mV)Peak firing frequency (Hz)n
Layer 6 pyramidal neurons–90.2 ± 0.6128.5 ± 3.983.1 ± 0.622.4 ± 0.8122
Layer 5 FS interneurons–85.2 ± 1.2114.3 ± 9.859.5 ± 2.2109.8 ± 23.319
Layer 5 nFS interneurons–82.7 ± 1.6235.9 ± 30.0*79.7 ± 1.9**34.1 ± 3.0**22
  • Neuronal properties shown are resting membrane potential (RMP), input resistance, spike amplitude, and peak firing frequency upon injection of a maximal suprathreshold current. Data are shown as mean ± SEM. Comparisons between L5 FS and nFS interneurons: *p < 0.05, **p < 0.001, unpaired t tests.