Wild-type (saline) | Wild-type (LPS) | Atm−/− (saline) | Atm−/− (LPS) | |
Cyclin A | 1.98 ± 0.96 | 1.48 ± 0.24 | 26.58 ± 2.30 | 38.0 ± 3.31* |
Cyclin D1 | 1.33 ± 0.97 | 1.48 ± 0.77 | 3.59 ± 1.09 | 6.09 ± 3.10 |
γ-H2AX | 2.58 ± 1.74 | 4.08 ± 2.34 | 6.53 ± 2.56 | 8.02 ± 0.95 |
Cleaved caspase 3 | 0 | 0 | 0 | 0 |
HDAC4 | 4.40 ± 2.27 | 7.13 ± 2.55 | 14.6 ± 0.36 | 22.2 ± 15.3 |
↵* Plus bold font = p < 0.05 compared with the Atm−/− group injected with saline.