PT  - JOURNAL ARTICLE
AU  - Mathilde Bonnefond
AU  - Sabine Kastner
AU  - Ole Jensen
TI  - Communication between Brain Areas Based on Nested Oscillations
AID  - 10.1523/ENEURO.0153-16.2017
DP  - 2017 Mar 01
TA  - eneuro
PG  - ENEURO.0153-16.2017
VI  - 4
IP  - 2
4099  - http://www.eneuro.org/content/4/2/ENEURO.0153-16.2017.short
4100  - http://www.eneuro.org/content/4/2/ENEURO.0153-16.2017.full
SO  - eNeuro2017 Mar 01; 4
AB  - Unraveling how brain regions communicate is crucial for understanding how the brain processes external and internal information. Neuronal oscillations within and across brain regions have been proposed to play a crucial role in this process. Two main hypotheses have been suggested for routing of information based on oscillations, namely communication through coherence and gating by inhibition. Here, we propose a framework unifying these two hypotheses that is based on recent empirical findings. We discuss a theory in which communication between two regions is established by phase synchronization of oscillations at lower frequencies (<25 Hz), which serve as temporal reference frame for information carried by high-frequency activity (>40 Hz). Our framework, consistent with numerous recent empirical findings, posits that cross-frequency interactions are essential for understanding how large-scale cognitive and perceptual networks operate.